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MRKH Syndrome & OLMEC Sigma-Lead Vaginoplasty
Understanding MRKH (Müllerian Agenesis)
MRKH syndrome, medically known as Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome, is a congenital reproductive condition affecting approximately 1 in 4,500 women worldwide. It is also referred to as Müllerian agenesis.
Women with MRKH are born with normal external genitalia, functioning ovaries, and normal female chromosomes (46,XX), but the uterus is absent or underdeveloped, and the vaginal canal may be shortened or absent.
Receiving a diagnosis of MRKH can feel overwhelming. Feelings of confusion, fear, sadness, or uncertainty are completely natural. With proper medical guidance and emotional support, women with MRKH can lead fulfilling lives, including healthy sexual relationships.
What Causes MRKH Syndrome?
MRKH is a congenital condition, meaning it develops during fetal growth. During embryonic development, the Müllerian ducts fail to fully form, resulting in absence or incomplete development of the uterus and upper vaginal canal.
The exact cause remains unknown. Current medical research suggests genetic and developmental factors may play a role, but no definitive origin has been identified.
Key Characteristics of MRKH
- Normal ovaries and hormone levels
- Absent or very small uterus
- Shortened or absent vaginal canal
- Normal vulva and external genitalia
- Normal breast development and puberty
Treatment Options for Vaginal Reconstruction
Women with MRKH who wish to have penetrative sexual intercourse have two primary options:
1. Non-Surgical Vaginal Dilation
Progressive vaginal dilation involves using medical dilators to gradually create a vaginal canal. This method requires consistent daily effort over several months.
- Non-invasive
- Requires long-term commitment
- May not result in self-lubrication
- Sensation may vary
2. OLMEC Sigma-Lead Vaginoplasty
The OLMEC Sigma-Lead vaginoplasty is an advanced surgical technique derived from traditional sigmoid colon vaginoplasty procedures. It utilizes a small segment of the rectosigmoid colon to create a fully functional vaginal canal.
This procedure aims to provide:
- Natural self-lubrication
- Full-depth vaginal canal (16–22 cm)
- Enhanced sensation
- Long-term structural stability
How the Sigma-Lead Vaginoplasty Works
The surgery is performed under general anesthesia. A small incision (5–7 cm) is made in the left groin. A 15–22 cm segment of the rectosigmoid colon is carefully selected and prepared as a graft.
Key Surgical Steps
- Inspection of blood supply to the sigmoid colon
- Harvesting a small rectosigmoid segment
- Reconnection of the remaining bowel
- Creation of a vaginal cavity between bladder and rectum
- Insertion and fixation of the graft
- Star-shaped suturing to prevent contraction
Because colon tissue naturally produces mild lubrication, the newly created vagina becomes self-lubricating over time.
Recovery & Post-Operative Care
Immediate Post-Op
- Hospital stay: 7–10 days (domestic patients)
- Overseas patients: Recommended 14-day stay
- IV antibiotics and pain management
- Catheter removal after 6–7 days
Dilation & Hygiene
- Dilation begins 5–7 days post-surgery
- Betadine wash hygiene for 3 weeks
- Use of sanitary pad during initial discharge period
Resuming Sexual Activity
Most patients can resume sexual intercourse approximately 6–8 weeks after surgery, depending on healing progress and medical evaluation.
Benefits of Sigma-Lead Vaginoplasty
- Self-lubricating vaginal canal
- High patient satisfaction rates
- Reduced contraction risk
- Natural feel and long-term durability
- Low infection rates with proper surgical protocol
Emotional & Psychological Support
A diagnosis of MRKH affects more than just physical health. Psychological counseling, support groups, and patient communities can significantly improve emotional well-being.
Consider connecting with:
- MRKH support groups
- Reproductive health counselors
- Gynecological specialists
Frequently Asked Questions (FAQ)
Can women with MRKH have biological children?
Women with MRKH have functioning ovaries. Biological motherhood may be possible through IVF and gestational surrogacy, depending on legal regulations.
Is Sigma-Lead vaginoplasty safe?
When performed by experienced surgeons using sterile bowel preparation and precise technique, complication rates are low and outcomes are highly favorable.
Schedule a Consultation
If you or a loved one has been diagnosed with MRKH syndrome and are exploring treatment options, our experienced surgical team is here to help.
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